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The Treatment

What is Polynucleotides?

Polynucleotides are purified DNA fragments used in aesthetic medicine to support the skin’s own regenerative processes. They are injected into the skin, where the aim is to improve hydration, elasticity and overall skin quality over a course of treatments.

They are often chosen for delicate areas such as under the eyes, and for skin that looks thin or crepey. Like other regenerative treatments, they work with the skin’s biology rather than adding volume, so the change is gradual and does not alter the shape of your face.

Key Benefits

What Polynucleotides can help with

  • Supports deep skin regeneration
  • Encourages the skin's own repair processes
  • Often chosen for the under-eye area
  • Given as a short course
  • Results build gradually over weeks

Suitability is assessed individually. Your practitioner will tell you honestly if a different treatment would suit you better, and individual results vary.

How It Is Done

What happens at your appointment

1

Consultation & assessment

We take a full medical history, assess the area and confirm the treatment is appropriate for you. Nothing is booked until we are satisfied it is suitable.

2

The treatment

The product is injected into the treatment area using a fine needle or cannula. Most appointments take under an hour.

3

Aftercare & review

You will be given written aftercare, and we follow up to see how your skin has responded before planning any further sessions.

Aftercare

  • Avoid touching or massaging the area unless advised.
  • Avoid make-up over injection points for the period advised.
  • No heat, saunas, steam or heavy exercise for 24–48 hours.
  • Mild swelling, redness or small bruises can occur.
  • Use SPF daily.
  • Contact us if you have any concerns.

Pricing & sessions

  • From £299 — confirmed at your free consultation.
  • 45–60 min appointment.
  • Course and package pricing is available on most treatments.
  • See the full price list for everything we offer.
Suitability

Is Polynucleotides right for you?

A good fit if…

  • Your skin looks thin, crepey or lacking elasticity
  • The under-eye area is a particular concern
  • You want a regenerative rather than volumising approach
  • You are happy for results to build gradually
  • You can commit to a course of sessions

Tell us first if…

  • You are pregnant or breastfeeding
  • You have an autoimmune condition or are immunosuppressed
  • You have an active infection or inflamed skin in the area
  • You have a known allergy to any component — discuss at consultation

Results and how often: A course is typical, usually around three sessions spaced two to four weeks apart, with the effect developing over subsequent months. Expect small bumps and possible mild bruising at injection points for a day or two. Everything starts with a free consultation, where price is confirmed.

Good To Know

Polynucleotides FAQs

How are polynucleotides different from Profhilo?
Both improve skin quality rather than adding volume. Profhilo is hyaluronic-acid based and works largely through hydration and bio-remodelling; polynucleotides are aimed at supporting the skin’s regenerative processes, and are often chosen for the under-eye area.
Can they be used under the eyes?
It is one of the more common uses, as the area is thin and does not always suit filler. Suitability is assessed at consultation.
Is there downtime?
Small raised bumps at the injection points settle within a day, and mild bruising is possible. Most people carry on as normal.
Does it hurt?
A fine needle is used and most clients find it very manageable. Your practitioner will discuss comfort options where appropriate.
Is there downtime?
Usually minimal, though small marks, swelling or bruising at the injection points can occur. We will tell you what to expect before you book.
How many sessions will I need?
Most injectable treatments work best as a short course. The exact number is agreed at your consultation.
Do I need a consultation first?
Yes. Every advanced treatment begins with a consultation so we can confirm it is appropriate for you and discuss realistic outcomes. It is free and there is no obligation.
Can you guarantee the result?
No, and we would be cautious of any clinic that does. We can tell you what this treatment typically achieves and what is realistic for you, but individual responses vary.
How do I book?
Book online at any time, message us on WhatsApp, or call 07391 213145. If you are unsure whether this is the right treatment, ask us first — we will point you to the right one.
Free Consultation  ·  No Obligation

Book your Polynucleotides consultation

We will assess your skin, discuss what you are hoping to achieve and recommend the treatment that genuinely suits you.

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